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Rainer Fietkau Selected Research

HMGB1 Protein (HMG1)

11/2023Radiotherapy combined with docetaxel alters the immune phenotype of HNSCC cells and results in increased surface expression of CD137 and release of HMGB1 of specifically HPV-positive tumor cells.
3/2016Primary glioblastoma multiforme tumors and recurrence : Comparative analysis of the danger signals HMGB1, HSP70, and calreticulin.
3/2016Erratum to: Primary glioblastoma multiforme tumors and recurrence: comparative analysis of the danger signals HMGB1, HSP70, and calreticulin.
1/2016Combination of ionising radiation with hyperthermia increases the immunogenic potential of B16-F10 melanoma cells in vitro and in vivo.
3/2014Fractionated radiotherapy is the main stimulus for the induction of cell death and of Hsp70 release of p53 mutated glioblastoma cell lines.
1/2010Application of hyperthermia in addition to ionizing irradiation fosters necrotic cell death and HMGB1 release of colorectal tumor cells.
5/2009Hyperthermia in combination with X-irradiation induces inflammatory forms of cell death.

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Rainer Fietkau Research Topics

Disease

147Neoplasms (Cancer)
03/2024 - 08/2004
46Breast Neoplasms (Breast Cancer)
03/2024 - 12/2005
39Rectal Neoplasms (Rectal Cancer)
07/2023 - 08/2004
29Neoplasm Metastasis (Metastasis)
12/2023 - 02/2006
29Hyperthermia
01/2023 - 11/2009
23Carcinoma (Carcinomatosis)
06/2022 - 01/2003
21Head and Neck Neoplasms (Head and Neck Cancer)
09/2023 - 01/2006
20Squamous Cell Carcinoma of Head and Neck
02/2024 - 01/2015
19Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2022 - 12/2003
17Pain (Aches)
01/2024 - 12/2005
13Melanoma (Melanoma, Malignant)
12/2023 - 11/2014
13Glioblastoma (Glioblastoma Multiforme)
12/2023 - 03/2014
12Brain Neoplasms (Brain Tumor)
03/2024 - 06/2008
11Small Cell Lung Carcinoma (Small Cell Lung Cancer)
02/2017 - 11/2002
9Prostatic Neoplasms (Prostate Cancer)
11/2023 - 08/2012
8Margins of Excision
04/2019 - 05/2011
7Adenocarcinoma
01/2023 - 04/2007
7Disease Progression
01/2023 - 02/2010
7Pancreatic Neoplasms (Pancreatic Cancer)
11/2021 - 07/2011
7Colorectal Neoplasms (Colorectal Cancer)
01/2017 - 03/2002
6Necrosis
02/2024 - 11/2004
6Pathologic Complete Response
10/2020 - 08/2006
6Urinary Bladder Neoplasms (Bladder Cancer)
12/2019 - 09/2008
5Glioma (Gliomas)
01/2023 - 12/2016
5Lung Neoplasms (Lung Cancer)
01/2022 - 12/2003
5Inflammation (Inflammations)
10/2019 - 05/2009
4Sarcoma (Soft Tissue Sarcoma)
12/2023 - 06/2006
4Noninfiltrating Intraductal Carcinoma (DCIS)
01/2023 - 11/2004
4Residual Neoplasm
01/2018 - 12/2003
3Squamous Cell Carcinoma (Epidermoid Carcinoma)
09/2023 - 06/2019
3Seizures (Absence Seizure)
01/2023 - 03/2012
3Pneumonia (Pneumonitis)
07/2022 - 12/2003
3Meningioma (Meningiomas)
03/2022 - 01/2017
3Esophageal Neoplasms (Esophageal Cancer)
01/2022 - 09/2013
3Paraganglioma (Paragangliomas)
01/2022 - 03/2014
3Nausea
12/2021 - 07/2012
3Vomiting
12/2021 - 07/2012
3Squamous Cell Neoplasms (Squamous Cell Cancer)
10/2021 - 01/2015
3Weight Loss (Weight Reduction)
12/2020 - 12/2003
3Ataxia Telangiectasia (Louis Bar Syndrome)
01/2020 - 12/2012

Drug/Important Bio-Agent (IBA)

17Cisplatin (Platino)FDA LinkGeneric
01/2023 - 12/2003
15Immune Checkpoint InhibitorsIBA
12/2023 - 01/2016
11Fluorouracil (Carac)FDA LinkGeneric
01/2022 - 12/2010
10Docetaxel (Taxotere)FDA Link
11/2023 - 10/2006
10Proteins (Proteins, Gene)FDA Link
01/2023 - 11/2010
10Hormones (Hormone)IBA
12/2022 - 07/2007
9Biomarkers (Surrogate Marker)IBA
01/2023 - 03/2016
9Oxaliplatin (Eloxatin)FDA LinkGeneric
01/2021 - 10/2010
8DNA (Deoxyribonucleic Acid)IBA
02/2024 - 01/2016
8Immune Checkpoint ProteinsIBA
12/2023 - 04/2020
7HMGB1 Protein (HMG1)IBA
11/2023 - 05/2009
7Carboplatin (JM8)FDA LinkGeneric
09/2022 - 12/2003
6Phosphotransferases (Kinase)IBA
02/2024 - 02/2018
6Programmed Cell Death 1 ReceptorIBA
01/2023 - 01/2016
6VaccinesIBA
02/2021 - 12/2009
6Irinotecan (Camptosar)FDA LinkGeneric
10/2016 - 03/2002
5RadonIBA
01/2024 - 03/2017
5durvalumabIBA
01/2023 - 01/2018
5PlatinumIBA
04/2022 - 04/2015
4Radiation-Sensitizing AgentsIBA
02/2024 - 01/2021
4Temozolomide (Temodar)FDA LinkGeneric
12/2023 - 01/2016
4Cadherins (E-Cadherin)IBA
11/2023 - 01/2017
4Cetuximab (Erbitux)FDA Link
01/2022 - 10/2010
4B7-H1 AntigenIBA
10/2021 - 01/2016
4Vinorelbine (Navelbine)FDA LinkGeneric
04/2016 - 12/2003
4HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA
03/2016 - 01/2015
4Peptides (Polypeptides)IBA
01/2016 - 01/2012
4CytokinesIBA
10/2014 - 06/2009
3AZD0156IBA
12/2023 - 01/2020
3GemcitabineFDA Link
01/2023 - 07/2011
3tremelimumabIBA
09/2022 - 10/2020
3LigandsIBA
04/2022 - 10/2010
3Capecitabine (Xeloda)FDA Link
01/2021 - 12/2007
3efavirenz (Sustiva)FDA Link
02/2018 - 08/2013
3Paclitaxel (Taxol)FDA LinkGeneric
01/2011 - 01/2006
2TOR Serine-Threonine KinasesIBA
02/2024 - 01/2020
21,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA
02/2024 - 12/2021

Therapy/Procedure

149Radiotherapy
03/2024 - 12/2003
96Therapeutics
03/2024 - 08/2004
82Chemoradiotherapy
11/2023 - 11/2002
44Drug Therapy (Chemotherapy)
01/2024 - 12/2003
24Neoadjuvant Therapy
01/2023 - 03/2006
23Brachytherapy
11/2023 - 05/2011
22Immunotherapy
01/2024 - 01/2012
10Segmental Mastectomy (Lumpectomy)
01/2023 - 11/2008
9Aftercare (After-Treatment)
12/2023 - 02/2006
9Induction Chemotherapy
09/2022 - 12/2010
6Adjuvant Chemotherapy
04/2020 - 01/2008
6Re-Irradiation
01/2020 - 03/2014
5Adjuvant Radiotherapy
12/2023 - 11/2004
5Catheters
09/2023 - 01/2018
5Particle Accelerators
12/2022 - 03/2012
4Consolidation Chemotherapy
01/2022 - 04/2006
4Cystectomy
12/2019 - 12/2012
4Combined Modality Therapy
12/2019 - 10/2011
3Palliative Care (Palliative Therapy)
11/2023 - 09/2008
3Radioimmunotherapy
01/2022 - 01/2018
3Prostatectomy (Retropubic Prostatectomy)
03/2021 - 10/2019
3Mastectomy (Mammectomy)
11/2019 - 08/2014
3Cranial Irradiation
01/2017 - 08/2006